The Use of Hyperbaric Oxygen Therapy for Radiation Cystitis

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Key Takeaways

  • Radiation cystitis is a serious long-term complication of pelvic radiation that can cause significant bleeding, repeated hospitalizations, transfusions, and a substantial decline in quality of life. Current treatment options often provide only temporary relief or carry meaningful risks.
  • Rather than simply managing symptoms, HBOT treats the underlying radiation damage by promoting new blood vessel growth, improving tissue oxygenation, reducing fibrosis, and supporting tissue repair.
  • A growing body of evidence demonstrates that HBOT significantly improves symptoms and quality of life for patients with radiation cystitis, particularly in patients who begin HBOT soon after symptom onset.
  • Clinical benefits have been shown to persist for years after treatment, while claims-based research suggests improved outcomes and lower total medical costs compared with standard care alone.